Endocrine Abstracts

Objective: Cushing’s disease (CD) accounts for approximately 80% of cases of Cushing’s syndrome. Its clinic is nonspecific and its diagnosis difficult. The objective of this study is to review the most frequent clinical signs of this disease in our environment and compare it with that described in the literature.Patients and methods: Retrospective descriptive study of patients with CD. We included all patients diagnosed with CD (2005–2017)...

Objective: The most used therapeutic guidelines for the induction of male puberty in hypogonadotropic hypogonadism (HH) are GnRH in subcutaneous pulsatile infusion and HCG in monotherapy or combined with FSH in intramuscular injection. The objective of this study was to evaluate the efficacy of subcutaneous HCG with or without FSH in induction of male puberty in patients with HH.Patients and methods: Descriptive study of patients with HH treated with HCG...

Objective: To evaluate the efficacy of dapagliflozin for glycemic control and progression of weight loss after stabilization with liraglutide 1.8 mg.Patients and methods: Descriptive study: patients with tipo 2 diabetes (DM-2) in treatment with metformin and liraglutide 1.8 mg, optimal metabolic control, which after stabilization in weight loss, liraglutide is suspended and dapagliflozin is added. Variables analyzed baseline and at 6 months after treatme...

Objective: To evaluate the efficacy of canagliflozin 100 mg for glycemic control and progression of weight loss after stabilization with liraglutide 1.8 mg.Patients and methods: Descriptive study: patients with type 2 diabetes (DM-2) in treatment with metformin and liraglutide 1.8 mg, optimal metabolic control, which after stabilization in weight loss, liraglutide is suspended and canagliflozin 100 mg is added. Variables analyzed baseline and at 6 months...

Objetive: The change of treatment of liraglutide 1.8 mg to dapagliflozin or canaglifonzin 100 mg in patients with optimal glycemic control and stabilization weight loss, achieves progression in weight loss and improves the metabolic control of the patient with tipo 2 diabetes (DM-2). Our objective is to evaluate if there are differences in metabolic control and progression of weight loss in patients treated with canagliflozin 100 mg or dapagliflozin.Pati...

Introduction: Obesity is a major health problem and a risk factor for the development of other diseases. However, there are morbid obese subjects of long evolution that can be considered metabolically healthy obese, whose existence is in doubt for many clinicians.Objetive: To analyze if there are differences in cardiovascular risk between metabolically healthy (MHO) and sick obese (MSO), matched by age, sex and body mass index (BMI).<p class="abstext...

Objectives: Pregnant women who are overweight or obese have an increased risk of complications during pregnancy, as do pregnant women with type 1 diabetes mellitus (DM1). The objective of this study is to describe the prevalence of overweight/obesity in pregnant women with DM1, and associated complications.Patients and methods: Retrospective descriptive study of pregnant women with DM1 (2004–2014). Variables analyzed: age, initial body mass index (B...

Objective: Obesity and overweight persist in patients with Cushing’s disease (CD) in remission, its persistence seems to be related to the duration of the disease. The aim of this study was to describe the persistence of overweight/obesity in patients with CD in remission and their relation to the duration of the disease.Patients and methods: Descriptive study of patients with CD (1995-2015). Variables analyzed: age, sex, body mass index (BMI), time...

Objective: Patients with Cushing’s disease (CD) may have adrenal nodules or hyperplasia related chronic hyperstimulation by adrenocorticotropic hormone (ACTH). The aim of this study was to describe the prevalence of adrenal nodules or hyperplasia in patients with CD and their relation with ACTH levels at diagnosis.Patients and methods: Descriptive study of patients with CD (1995–2015). Variables analyzed: age, sex, body mass in...

Objective: Diagnosis of diabetes after transplantation (NODAT) has been described in up to 25% of cases. NODAT is a metabolically complex disorder, similar to type 2 diabetes. Factors that influence the development of NODAT are: BMI, HCV and immunosuppression. Objective: to know the prevalence and incidence of diabetes mellitus (DM) in liver transplant patients of our hospital.Patients and methods: Retrospective descriptive study of liver transplant pati...